Adverse effects are possible when taking coreg.
The concomitant administration of amiodarone or other cyp2c9 inhibitors such as fluconazole with coreg may enhance the -blocking activity resulting in further slowing of the heart rate or cardiac conduction.
Coreg may be used with caution, however, in patients who do not respond to, or cannot tolerate, other antihypertensive agents.
Of the 1,156 subjects randomized to coreg in a long term, placebo controlled trial in severe heart failure, 47 547 were aged 65 years or older, and 15 174 were aged 75 years or older.
There were no reports of bradycardia in the clinical trial of coreg cr in hypertension.
Indications dosage of coreg.