Metformin moderate sulfonamides may induce hypoglycemia in some patients by increasing the secretion of insulin from the pancreas.
In prostate cancer, the metformin active surveillance trial nct01864096 , an ongoing randomised phase iii trial of metformin versus placebo given before primary therapy is assessing time to progression in men with low-risk prostate cancer.
In controlled clinical trials, pioglitazone had an additive effect on glycemic control when used in combination with a sulfonylurea, metformin, or insulin see clinical studies .
Alogliptin metformin is a member of the antidiabetic combinations drug class and is commonly used for diabetes – type 2.
There was no evidence of a mutagenic potential of glycomet gp metformin hydrochloride in the following in vitro tests ames test s.